The Perfect Pill

Formulated to Nutritionally Support Healthy Blood Sugar Levels.

This formula utilizes nutrients in the most absorbable and potent form available. Most companies compromise the nutrients by utilizing poorly absorbed forms or synthetically derived fractions of the specific nutrients research has shown to be effective.

This information represents the nutrients found in the formulas Peer Reviewed Research. We do not claim to cure or prevent any disease. We recommend you consult your doctor before changing your diet, medication, or exercise program.

The Perfect Pill™
Formulated to Nutritionally Support Healthy Blood Sugar Levels.

Blood Sugar

Vitamin C

Vitamin C has been shown to nutritionally help maintain healthy blood sugar levels.

Magnesium

Magnesium is involved in helping maintain healthy glucose metabolism (1). Many Americans tend to fall below the RDA for magnesium intake by 70-80mg. Many experts feel the RDA for magnesium needs to be significantly increased from the current level of 350mg to as much as 700mg per day.

1 Elamin A, et al. Magnesium and insulin-dependent diabetes mellitus. Diabetes Res Clin Pract. 1990;10(3):203-9.

Chromium

The influence of chromium on helping maintain healthy blood sugar was first recognized in animal studies in the 1950s. In the 1970s, chromium's importance was discovered. Various studies support that chromium has a positive effect on helping maintain healthy blood glucose levels (3).

Several groups are at risk for reduced chromium levels. First of all, most Americans are at risk because of a diet rich in refined sugars. Individuals who eat diets high in refined sugars tend to excrete 300 percent more chromium in their urine than those whose diets are low in refined sugars. People who exercise regularly excrete two to six times the normal amount of chromium in their urine on days of exercise (5). Many athletes compound this problem with high-carbohydrate supplements. The elderly also tend to be at risk due to reduced absorption and inadequate intake of chromium. It is interesting to note that women tend to have a drop in chromium levels during the third trimester of pregnancy (6).

There is a great deal of controversy over what is the best chromium to use. Chromium is biologically active only in the trivalent state in which it forms complexes with organic compounds. The most important of these complexes is glucose tolerance factor (GTF), which is comprised of trivalent chromium, niacin, glycine, glutamic acid, and cysteine. Organically bound GTF chromium is thought to be safe and well tolerated.

Chromium picolinate is another popular form of chromium that has helped maintain healthy blood sugar regulation (7). The majority of evidence points to the safety of the picolinate form.

With lifestyle and dietary changes, there may not be a need for an aggressive chromium dosage.

3 Studies presented at the Annual Scientific Sessions of the American Diabetes Association. San Francisco, CA. 1996.
4 Vincent JB. Mechanisms of chromium action: low-molecule-weight chromium-binding substance. J Am Coll Nutr. 1999;18(1):6-12.
5 Anderson RA. Chromium as an essential nutrient for humans. Reg Tox Pharmacol. 1997;26:S35-S46.
6 Saner G. Urinary chromium excretion during pregnancy and its relationship with intravenous glucose loading. Am J Clin Nutr. Sep1981;34(9):1676-9.
7 Evans GW. The effect of chromium picolinate on insulin controlled parameters in humans. Int J Biosocial Med Research. 1989;11(2):163-80.

Gymnema

Gymnema is a rain forest vine found in Central and Southern India, which has a long tradition in nutritionally supporting healthy blood glucose levels. The Indian name is Gurmar, which means, "sugar destroyer." Its use has been documented in Ayurvedic medical texts for over 2,000 years in the treatment of "sweet urine." Gymnema is gaining popularity with clinicians utilizing natural therapy protocols for helping maintaining healthy blood glucose levels.

Gymnema reportedly produced blood glucose homeostasis and increased the activity of the enzymes involved in the utilization of glucose pathways (40).

Gymnema has also been reported to selectively suppress the neural responses to sweet taste stimuli (44),(45),(46). Because gymnema leaf powder has an anesthetizing effect on the taste buds which can last for several hours, some researchers feel that gymnema may be a potential agent in helping maintain healthy body weight and sweet cravings (47). Gymnema may potentially be used in athletes to develop a higher ratio of lean muscle mass to body fat. Another study found that gymnema was effective in supporting a healthy body weight (49).

40 Shanmugasundaram KR, et al. Enzyme Changes and Glucose Utilization in Diabetic Rabbits: The Effect of Gymnema sylvestre, R.Br. J Ethnopharmacol. Mar1983;7(2):205-34.
41 Baskaran K, et al. Antidiabetic Effect of a Leaf Extract from Gymnema Sylvestre in Non-insulin-dependent Diabetes Mellitus Patients. J Ethnopharmacol. Oct1990;30(3):295-300.
42 Shanmugasundaram ER, et al. Use of Gymnema sylvestre Leaf Extract in the Control of Blood Glucose in Insulin-dependent Diabetes Mellitus. J Ethnopharmacol. Oct1990;30(3):281-94.
43 Shimizu K, et al. Suppression of Glucose Absorption by Extracts From the Leaves of Gymnema inodorum. J Vet Med Sci. Sep1997;59(9):753-57.
44 Kamei K, et al. Amino Acid Sequence of Sweet-taste-suppressing Peptide (Gurmarin) from the Leaves of Gymnema sylvestre. J Biochem (Tokyo). Jan1992;111(1):109-12.
45 Imoto T, et al. A Novel Peptide Isolated from the Leaves of Gymnema sylvestre - I. Characterization and Its Suppressive Effect on the Neural Responses to Sweet Taste Stimuli in the Rat. Comp Biochem Physiol A. 1991;100(2):309-14.
46 Kurihara Y. Characteristics of Anti-sweet Substances, Sweet Proteins, and Sweetness-inducing Proteins. Crit Rev Food Sci Nutr. 1992;32(3):231-52.
47 Brala PM, et al. Effects of Sweetness Perception and Caloric Value of a Preload on Short Term Intake. Physiol Behav. Jan1983;30(1):1-9.
49 Preuss HG, Bagchi D, Bagchi M, Rao CV, Dey DK, Satyanarayana S. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab. May2004;6(3):171-80.

Bitter Melon

Bitter melon or karela fruit has long been used in South American and the Orient as not only a food but also to nutritionally support the body in many healthful ways. It is recommended that a standardized extract of bitter melon always be used.

Evening Primrose (Omega Fatty Acids)

Evening primrose oil (EPO) is rich in gamma-linolenic acid which is an omega-6 fatty acid (30), (31). Supplementation with essential fatty acids such as EPO has been reported to help maintain healthy zinc levels (32). Fatty acids are an important part of normal homeostasis. The human body can produce all but two fatty acids - omega-3 and omega-6 fatty acids. Both must be obtained through the diet or by the use of supplements. Obtaining a balance of these two fatty acids is essential. Essential fatty acids are needed for helping maintain healthy cell membranes. Modern diets tend to be lacking in quality sources of fatty acids.

30 Chapkin RS, et al. Dietary Influences of Evening Primrose and Fish Oil on the Skin of Essential Fatty Acid-deficient Guinea Pigs. J Nutr. 1987;117(8):1360-70.
31 Dutta-Roy AK, et al. Effects of Linoleic and Gamma-linolenic Acids (Efamol Evening Primrose Oil) on Fatty Acid-binding Proteins of Rat Liver. Mol Cell Biochem. 1990;98(1-2):177-82.
32 Dib A, et al. Effects of Gamma-linolenic Acid Supplementation on Pregnant Rats Fed a Zinc-deficient Diet. Ann Nutr Meta. 1987;31(5):312-19.

Fish Oil

Fish oil is shown to support the body nutritionally for several reasons. Fish oil is derived from the tissues of oily fish and naturally contains the Omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Fish oil is recommended for a helping maintain a healthy diet.

Vanadium

This is another trace element used to help nutritionally support the body's healthy blood glucose levels. It's an important component of some enzymes